PHARMA THIRD PARTY CONTRACT MANUFACTURER OF DICLOFENAC, PARACETAMOL & SERRATIOPEPTIDASE
Diclofenac, Paracetamol & Serratiopeptidase fusion is formulated in order to avoid the administration of these three Brands individually. Diclofenac & paracetamol are NSAID’s (Non-steroidal anti-inflammatory) Diclofenac shows anti-inflammatory & antipyretic action & paracetamol shows analgesic & antipyretic action & Serratiopeptidase is a proteolytic enzyme contribute for reduce pain & swelling.
Class- NSAIDs, Analgesic, Antipyretic & proteolytic enzyme
Mechanism of Action
The motive of this combination is to reduce fever, pain and inflammatory reactions. Paracetamol lowers the fever by direct action on the thermoregulatory center in the hypothalamus. Serratiopeptidase reduces the swelling. Diclofenac inhibits cyclo-oxygenase which is important for the prostaglandin synthesis.
Absorption-This product is rapidly & completely absorbed.
The Onset of action of the product - 30-60 minutes.
Duration of action - 6-12 hours
Plasma protein binding- Diclofenac- less than 99%
Plasma protein binding- Paracetamol-less than 20%
The half-life of Diclofenac-2 hours
The half-life of Paracetamol-1-4 hours
Excretion- After hepatic metabolism metabolites are excreted through kidney in urine.
The combination of these products can be prescribed as Anti-inflammatory, Anti swelling, anti-rheumatoid in bronchitis, sprains, fever, cough & cold, sinusitis, gout, sports injury, migraine, Headache & muscle pain, Sore throat, ear infections etc.
Side Effects of Diclofenac, Paracetamol & Serratiopeptidase
Adverse effects of this combination are
Diarrhea & rashes
Acute renal failure
Epigastric pain & nausea
Wheezing & bronchospasm
This combination can interfere with
Cholestyramine- it reduces the absorption of paracetamol.
Potassium-sparing diuretics-reduces salicylate serum level
Dosage- For a dose, recommendation consult with your healthcare professional.
We are the supplier Diclofenac, Paracetamol & Serratiopeptidase & also a trader of Diclofenac, Paracetamol & Serratiopeptidase.
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