General Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF DICLOFENAC, PARACETAMOL & SERRATIOPEPTIDASE

Introduction


Diclofenac, Paracetamol & Serratiopeptidase fusion is formulated in order to avoid the administration of these three Brands individually. Diclofenac & paracetamol are NSAID’s (Non-steroidal anti-inflammatory) Diclofenac shows anti-inflammatory & antipyretic action & paracetamol shows analgesic & antipyretic action & Serratiopeptidase is a proteolytic enzyme contribute for reduce pain & swelling.

Class- NSAIDs, Analgesic, Antipyretic & proteolytic enzyme

Mechanism of Action 

The motive of this combination is to reduce fever, pain and inflammatory reactions. Paracetamol lowers the fever by direct action on the thermoregulatory center in the hypothalamus. Serratiopeptidase reduces the swelling. Diclofenac inhibits cyclo-oxygenase which is important for the prostaglandin synthesis. 

Pharmacokinetics 

Absorption-This product is rapidly & completely absorbed. 

The Onset of action of the product - 30-60 minutes.

Duration of action - 6-12 hours

Plasma protein binding- Diclofenac- less than 99%

Plasma protein binding- Paracetamol-less than 20%

The half-life of Diclofenac-2 hours 

The half-life of Paracetamol-1-4 hours

Excretion- After hepatic metabolism metabolites are excreted through kidney in urine.

Pharmacological Uses

The combination of these products can be prescribed as Anti-inflammatory, Anti swelling, anti-rheumatoid in bronchitis, sprains, fever, cough & cold, sinusitis, gout, sports injury, migraine, Headache & muscle pain, Sore throat, ear infections etc.

Side Effects of Diclofenac, Paracetamol & Serratiopeptidase

Adverse effects of this combination are 

Gastrointestinal bleeding/disturbance 

Diarrhea & rashes 

Anorexia 

Nephrotic syndrome

Acute renal failure

Epigastric pain & nausea

Wheezing & bronchospasm

product interaction 

This combination can interfere with 

Cholestyramine- it reduces the absorption of paracetamol. 

Potassium-sparing diuretics-reduces salicylate serum level

Dosage- For a dose, recommendation consult with your healthcare professional. 

We are the supplier Diclofenac, Paracetamol & Serratiopeptidase & also a trader of Diclofenac, Paracetamol & Serratiopeptidase.

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DICLOFENAC 50mg, PARACETAMOL 325mg, SERRATIOPEPTIDASE 15mg Tablet ALU-ALU 10*10