PHARMA THIRD PARTY CONTRACT MANUFACTURER OF DICLOFENAC, SERRATIOPEPTIDASE, PARACETAMOL
This is the combination possessing following actions Anti-inflammatory, Anti swelling, anti-rheumatoid and also controls pain and maintains body temperature.
NSAIDs, Analgesic, Antipyretic & proteolytic enzyme
Mechanism of action
The motive of this combination is to reduce fever, pain and inflammatory reactions. Paracetamol lowers the fever by direct action on the thermoregulatory center in the hypothalamus. Serratiopeptidase reduces the swelling. Diclofenac inhibits cyclo-oxygenase which is important for the prostaglandin synthesis.
The Absorption of this combination is rapid & completely absorbed in GIT. The Onset of action and Duration of action of the two products is 30-60 minutes and 6-12 hours respectively and of Serratiopeptidase is 30-60 minutes and 8-10 hours. The Plasma protein binding of Diclofenac is less than 99% and Paracetamol is less than 20% similarly their Half-lives are 2 hours and 1-4 hours respectively. Excretion- After hepatic metabolism metabolites are excreted through kidney in urine.
The therapeutic uses of this combination are
Fever, cough & cold
Sports injury, migraine, Headache & muscle pain
A sore throat, ear infections
The adverse reactions with this are gastrointestinal bleeding/disturbance, Diarrhea & rashes, Anorexia, Nephrotic syndrome, acute renal failure, Epigastric pain & nausea and Wheezing & bronchospasm
The whole combination can interfere with the Cholestyramine by reducing the absorption of paracetamol and other is Potassium-sparing diuretics which can reduce salicylate serum level.
As per the recommendation of your healthcare professional and pharmacist.
We are the supplier Diclofenac, Paracetamol & Serratiopeptidase & also a trader of Diclofenac, Paracetamol & Serratiopeptidase.
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