General Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF LEVOCETIRIZINE, PHENYLEPHRINE & PARACETAMOL

Introduction

The combination of these three active products is designed in order to avoid the individual administration of these products. This is the perfect combination of an antihistaminic product that is Levocetirizine used against the allergic symptoms, an analgesic & antipyretic product that is Paracetamol for pain & fever management & a Decongestant that is Phenylephrine used to remove the blockage in airways. 

Class Antihistamine, Analgesic & Antipyretic, Decongestant

Mechanism of Action

The therapeutic action of Paracetamol as an analgesic can be seen by elevating the pain threshold & anti-pyretic effect by blocking the effects produced by endogenous pyrogen. Phenylephrine action is an agonist of the Alpha-1-adrenergic receptor & Levocetirizine works by the cut off the histamine binding to the receptor which is essential for allergy.

Pharmacokinetics

Absorption of combination-Rapidly (oral)

Bioavailability of Phenylephrine-38%

Protein binding of Levocetirizine-91-92%

Protein binding of Paracetamol- 25%

Protein binding of Phenylephrine-95%

A half-life of Levocetirizine-8-9 hours 

A half-life of Paracetamol -1-4 hours

A half-life of Phenylephrine-2.1-3.4 hours                 

Pharmacological Uses

The fusion of Levocetirizine, Paracetamol, and Phenylephrine may be prescribed for the prevention of various illness like allergic disorder, dust & pet allergies, swelling on the skin, Ear-round allergies, fever, & pain, Ear pain, joint pain, Headache & also used as a nasal decongestant. 

Side Effects

Dry mouth

Insomnia 

Itching & redness

Skin Rashes

Drowsiness

Fatigue 

Dry mouth 

Gastric disturbance 

Tingling

product Interaction 

The products which may interact with this combination are 

Ketoconazole

Prilocaine 

Theophylline

Ritonavir 

Clotrimazole (decreases metabolism)

Alcohol & laboratory tests

Dosage

Each tablet contains Levocetirizine 5mg, Phenylephrine 10mg & Paracetamol 500mg

We are the supplier Levocetirizine, Paracetamol, and Phenylephrine & also a trader of Levocetirizine, Paracetamol, and Phenylephrine.

* The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.