PHARMA THIRD PARTY CONTRACT MANUFACTURER OF MEFENAMIC ACID & DROTAVERINE HCL
Mefenamic acid is a member of NSAID's (Non-steroidal anti-inflammatory) which possess anti-inflammatory with analgesic action used against swelling & pain in the body. Drotaverine is classified as antispasmodic product similar to papaverine.
Class-NSAID's & Antispasmodic
Mechanism of action
Mefenamic acid works on the principal of NSAID’s that is it inhibits the action of cyclooxygenase enzyme which catalysis the prostaglandin (responsible for pain & inflammation) synthesis. Drotaverine HCl inhibits phosphodiesterase enzyme IV which decreases cyclic AMP & calcium ions as a result of which blood vessel get dilate against spasm.
Absorption-Rapidly or well absorbed
The onset of action- Mefenamic acid-1-2 hours
The onset of action-Drotaverine-30 minutes
Duration of action-Mefenamic acid-6 hours
Duration of action Drotaverine-4 hours
Protein binding of Mefenamic acid-90%
Protein binding of Drotaverine-80-95%
The Half-life- Mefenamic acid -2-4 hours
The half-life of Drotaverine-7-12 hours
Mefenamic acid & Drotaverine combination can be prescribed in Dysmenorrhea, Post-surgical uterine spasm, Gastrointestinal colic, Renal colic, biliary colic, Uterine irritability, Pain associated with IUCD insertion, PID or HSG, Heavy bleeding during periods, fever, migraine headache.
Nausea & sweating
Irregular heart rhythm
The products which can interfere with the action of Mefenamic acid & Drotaverine are
One tablet is taken every 6-8 hours or consults with your doctor or pharmacist (healthcare professional).
We are the supplier of Mefenamic acid & Drotaverine HCL & also a trader of Mefenamic acid & Drotaverine HCL.
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