PHARMA THIRD PARTY CONTRACT MANUFACTURER OF RABEPRAZOLE & ITOPRIDE
Rabeprazole is organized as a member of a group of Proton pump inhibitor which is usually prescribed for suppressing the amount of gastric acid to prevent the stomach from ulcers. Itopride is derived from the benzamide & is an antagonist of dopamine receptor which is used to stimulate the gastric movement.
Class Proton pump inhibitor & Dopamine receptor antagonist
Mechanism of action
Rabeprazole is an antisecretory compound which functions to suppress the amount of gastric acid by inhibiting the functioning of H+/K+-ATPase system which gets activated in acidic medium. Itopride works by inhibiting Dopamine receptor & by inhibiting the enzyme acetylcholinesterases which raise the release & minimize the metabolism of Acetylcholine.
Absorption of combination-Rapid
Metabolism of combination-Hepatic
Bioavailability of Rabeprazole - 52%
Protein binding of Rabeprazole-96.3%
The half-life of Rabeprazole-1-2 hours
The half-life of Itopride-5-6 hours
The combination of Rabeprazole & Itopride is prescribed for the functional dyspepsia, Stomach acid, duodenal ulcers, and gastrointestinal problems, smooth emptying of stomach, irritable bowel syndrome and gastrointestinal reflux disease.
Dizziness & Headache
Diarrhea & rashes
Sore & dry throat
Rhinitis & insomnia
Feeling of irritation
Atropine (therapeutic efficacy increases)
Antipyrine (its metabolism decreases)
Benzyl alcohol (its metabolism decreases)
Caffeine (its metabolism decreases)
Amphetamine (its absorption increases)
Cimetidine (metabolism decreases)
Each capsule contains 20mg Rabeprazole of & 150mg of Itopride. The dose recommended is 1-2 capsules per day or as suggested by the healthcare professional.
We are the supplier of Rabeprazole & Itopride & also a trader of Rabeprazole & Itopride.
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