General Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF MONTELUKAST & FEXOFENADINE

Introduction


Montelukast is classified as an antagonist of leukotriene receptor which is used to get relief from asthma & decreases bronchoconstriction. Fexofenadine falls into the category of Antihistamines of the second generation which is used against allergic symptoms to prevent the body.

Class leukotriene antagonist & Antihistamines

Mechanism of action

Montelukast works to prevent airway edema by its antagonistic action that is by inhibiting leukotriene D4 at its binding site which cysteinyl leukotriene receptor is resulting in contraction of smooth muscle. Fexofenadine works by fighting with free histamines for inhibition of its binding at Histamine (H1) receptor resulting in the blockage of histamine action on the body. 

Pharmacokinetics

Absorption of product-Rapidly (oral)

Protein binding of Montelukast-99%

Protein binding of Fexofenadine-60-70%   

The half-life of Montelukast-2.7-5.5 hours

The half-life of Fexofenadine-14.4 hours

Pharmacological Uses

The combination of Montelukast & Fexofenadine is used for the prevention of allergic rhinitis, Asthma, seasonal allergies, in the treatment of hay fever, chronic allergy (chronic idiopathic urticaria).

Side Effects

Dizziness 

Drowsiness 

Dry mouth 

Chest tightness

Swelling of face, lips, tongue, Hands & Legs 

Hypersensitivity

Abdominal discomfort

product Interactions

Alprazolam (adverse reaction produces) 

Aluminum glycinate/hydroxide (decreases serum concentration) 

Butacaine, Butabarbital (adverse reaction produces) 

Amiodarone (its serum concentration increases)

Theophylline & Alcohol 

Dosage

For a dose, recommendation consults with your doctor or pharmacist (healthcare professional) 

We are the supplier of Montelukast & Fexofenadine & also a trader of Montelukast & Fexofenadine.

*The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.


MONTELUKAST SODIUM 10mg, FEXOFENADINE 120mg Chewable Tablet ALU-ALU 10*10