PHARMA THIRD PARTY CONTRACT MANUFACTURER OF CEFIXIME & AZITHROMYCIN
The motive of manufacturing the merger of broad-spectrum antibiotics is to fight against that bacteria which is responsible for the dreadful infection. Both agents are equally important in terms of curing. Cefixime is classified as cephalosporin antibiotic of the third generation whereas Azithromycin as Macrolide antibiotics of Azalide group. Class- cephalosporin & Macrolide antibiotics???????
Mechanism of Action
Cefixime targets the third & final step of cell wall preparation by the bacteria by sticking to penicillin-binding proteins & resistance to beta-lactamase, however, Azithromycin combines with 50S ribosome of bacteria which interferes translocation of mRNA & thereby helps to stop the protein synthesis of bacteria.
Bioavailability of Cefixime-40-50%
Bioavailability of Azithromycin-37%
Protein binding of Cefixime approximately 60%
Protein binding of Azithromycin-Near about 51% (it can be available)
A half-life of Cefixime 3-4 hours
A half-life of Azithromycin-68 hours
As it is a combination of antibiotic so it is advised to be taken in bacterial infection like upper & lower respiratory tract infection, acute sinusitis, urinary tract infection, strep throat, typhoid, Middle ear infection, Chronic bronchitis & Otitis media.
Inflammation of face or tongue
Color alteration in urine & stools
Irritation of eyes
Albendazole, Almotriptan (their metabolism decreases)
Atorvastatin (its serum concentration increases)
Carbamazepine (metabolism of Azithromycin increases)
Warfarin & Acenocoumarol (its anticoagulant activity increases)
Probenecid (increases serum concentration)
For a dose recommendation, consult your healthcare professional.
We are the supplier of Cefixime & Azithromycin & also a trader of Cefixime & Azithromycin.
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