Antibiotics Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF AMOXICILLIN & DICLOXACILLIN

Introduction


This is an effective combination of antibiotics to work against infections caused by bacteria. Amoxycillin is derived from the aminopenicillin & is a semisynthetic form of beta-lactam antibiotics to show broad-spectrum action.  Dicloxacillin is used against the penicillinase & is also a beta-lactam antibiotic which shows narrow spectrum action. 

Class Beta-lactam antibiotics

Mechanism of action

All the penicillin antibiotics target the cell wall of bacteria. Amoxicillin works by inhibiting the bacteria to make its cell wall which is necessary for their protection by binding to the PBP-1 (penicillin-binding protein). All this stop the bacteria from multiplying. Dicloxacillin inhibits the final step of bacterial cell wall formation by inhibiting cross-linkage between linear peptidoglycan polymer chains. 

Pharmacokinetics

Absorption of Amoxycillin & Dicloxacillin--well absorbed (oral)

Protein binding of Amoxicillin-20%

Protein binding of Dicloxacillin-96%

Metabolism of Amoxicillin-Hepatic metabolism 

The half-life of Amoxicillin-61.3 hours

The half-life of a Dicloxacillin-0.7 hour 

Pharmacological Uses

The combination of Amoxycillin & Dicloxacillin can be prescribed for the Respiratory tract infection, Otitis media, acute & chronic bronchitis, lung abscess, bronchiolitis, infection associated with the gynecological infections, urethritis. It may be prescribed for serious infections, brain abscess & bacterial meningitis & also bone infections. 

Side Effects

Thrombocytopenia 

Anaphylaxis 

Nephritis 

Seizure 

Nausea & Diarrhea 

Increase in liver enzymes 

Superinfection 

Urticaria 

product Interactions

Sulfonamides 

Chloramphenicol 

Aminoglycosides 

Amikacin, Acemetacin & Cimetidine 

Gentamicin

Methotrexate & Minocycline 

Dosage

For a dose, recommendation consults with your doctor or pharmacist (healthcare professional).

We are the supplier of Amoxycillin & Dicloxacillin & also a trader of Amoxycillin & Dicloxacillin.

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AMOXYCILLIN 250mg, LACTIC ACID BACILLUS , DICLOXACILLIN 250mg Capsule ALU-ALU 10*10