PHARMA THIRD PARTY CONTRACT MANUFACTURER OF AMLODIPINE & TELMISARTAN (Tablet)
Amlodipine besylate belongs to the family of calcium channel blocker for lowering the blood pressure in hypertension. Telmisartan belongs to the angiotensin II receptor blocker by loosening up the blood vessels to prevent the blood flow & make it easy to flow.
calcium channel blocker & angiotensin II receptor blocker
Mechanism of action
Amlodipine works on the principle of blocking the calcium ion influx across the cell membrane due to which vasodilatation occurs & peripheral vascular resistance decreases to lower the blood pressure. Telmisartan works by inhibiting angiotensin II receptor type 1 that is AT1 with greater affinity as compared to AT2 in vascular smooth muscles & adrenal glands.
Absorption- Amlodipine-Slowly but completely absorbed from GIT.
Bioavailability of Amlodipine-64-90%
Bioavailability of Telmisartan-60% (40mg)
Protein binding of Amlodipine-97.5%
Protein binding of Telmisartan-99.5%
A half-life of Amlodipine-30-50 hours
A half-life of Telmisartan-24 hours
Amlodipine & Telmisartan is used for the Hypertension to lower the blood pressure, Kidney failure in a patient with diabetes, Heart attack, Heart failure, chronic stable angina, Vasospastic angina, Prevent Strokes & coronary artery disease.
Unusual tiredness or weakness
Swelling of legs & feet
Difficulty during Breathing
Digoxin & ramipril
As recommended by your doctor or pharmacist.
We are the supplier of Amlodipine & Telmisartan & also a trader of Amlodipine & Telmisartan.
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