PHARMA THIRD PARTY CONTRACT MANUFACTURER OF AMLODIPINE & ATENOLOL (Tablet)
The combination is designed to lessen the workload (pump) of Heart. As their combination therapy proves better than monotherapy. Amlodipine is a part of the family calcium channel blocker for lowering the blood pressure in hypertension. Atenolol is a Beta-1 receptor antagonist belongs to the beta blockers for cardiovascular disease.
Class Calcium channel blocker & Beta-blockers
Mechanism of Action
Amlodipine works on the principle of blocking the calcium ion influx across the cell membrane due to which vasodilatation occurs & peripheral vascular resistance decreases to lower the blood pressure whereas Atenolol works on the principle of binding at Beta-1 adrenergic receptors for the reduction in resting heart rate, cardiac output, Systolic & diastolic blood pressure.
Absorption- Amlodipine -Slowly but completely absorbed from GIT.
Absorption-Atenolol-50% absorbed from GIT.
Bioavailability of Amlodipine-64-90%
Protein binding of Amlodipine-97.5%
Protein binding of Atenolol-6-16%
A half-life of Amlodipine-30-50 hours
A half-life of Atenolol-6-7 hours
Amlodipine & Atenolol combination may be prescribed for the management for lowering blood pressure in Hypertension, Coronary artery disease, chronic stable angina, Vasospastic angina, Myocardial infarction & chest pain.
Swelling of legs & feet
Dizziness & Drowsiness
Worsening chest pain
Each tablet contains Amlodipine 5mg & Atenolol 50mg. Consult with your Doctor or Pharmacist.
We are the supplier of Amlodipine & Atenolol & also a trader of Amlodipine & Atenolol.
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