Cardiac/Diabetic Products



Amlodipine Besylate is a part of the family calcium channel blocker for lowering the blood pressure in hypertension. They work to lessen the workload (pump) of Heart by relaxing the blood vessels & are a long-acting product. It increases the input of blood to the heart to suppress the chest pain.

Class Calcium channel blocker

Mechanism of Action

Amlodipine works on the principle of blocking the calcium ion influx across the cell membrane on vascular smooth muscle cells with a greater effect as compared to cardiac muscle cells. As a result, vasodilatation occurs & peripheral vascular resistance decreases to lower the blood pressure. 


Absorption-Slowly but completely absorbed from GIT. 

Bioavailability of Amlodipine-64-90%

Protein binding of Amlodipine-97.5%

The half-life of Amlodipine-30-50 hours

Pharmacological Uses 

Amlodipine is used for the management of high blood pressure, coronary artery disease, Heart-related chest pain, chronic stable angina, Vasospastic angina, Prevent Strokes. 

Side Effects


Peripheral edema

Swelling of legs & feet

Stomach pain

Dizziness & Drowsiness

Worsening chest pain

product Interaction 

There are a number of products which can interact with the Amlodipine 

Alprenolol, Acebutolol (its hypotensive action increases)

Alfuzosin, Amphetamine (increases hypotensive action)

Amphotericin B, Amorolfine (adverse effects)

Barbexaclone, Barbital (Increases metabolism)


Starting dose-5mg OD (once a day)

Maintaining does-5-10mg OD (once a day)

The dose should not exceed 10mg per day. For the fragile patient, 2.5mg is enough.

We are the supplier of Amlodipine & also a trader of Amlodipine.

* The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.


AMLODIPINE BESYLATE 2.5mg Tablet Blister 10*10